GRCh38 / hg38Genome Reference
3.09 GbGenome size
24Chromosomes
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2
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22
X
Y
M
Isochores
L1
L2
H1
H2
H3
AT-rich → GC-richToolkit
06 Modules01 / Module
EVALUATE
Physics linter for synthetic constructs
13 flag types · batch mode · 4 bots
AUROC 0.827 for crossover hotspot discrimination
02 / Module
TRANSPOSOME
LINEs · SINEs · LTRs · ERVs
4.6M elements · 23 claims · 3 bots
SINEs +0.18 vs gene expression, GC-independent
03 / Module
HLA
Allele biophysics & expression
3 classical loci · 12 claims · 2 bots
HLA-A dG37 vs TPM r = −0.76
04 / Module
CLOCKS
Epigenetic aging & biomarkers
~15 clock models · 8 claims
CDI ≈ ThermAge on 450K arrays, r = 0.9991
05 / Module
DMP
Differential methylation probes
860K probes · 5 claims
DMP lists annotated with biophysics in one call
06 / Module
TE METHYLATION
TE-resolved CpG context
~800K TE-resolved CpGs · 9 claims
Universal erosion floor 0.15 obs/exp across TE families